CJC-1295 (Without DAC)
Synthetic 30-amino acid analogue of GHRH(1-29). Mass-spec certified, lyophilized, research-grade.
Third-party tested, batch-by-batch
Every lot is independently verified for identity (MS), purity (HPLC), appearance, and endotoxin. View the summary for the current lot, or request the full signed PDF by email.
Frequently researched together
Technical specifications
CJC-1295 (with DAC) is a synthetic peptide analogue of Growth Hormone-Releasing Hormone (GHRH), a 44-amino-acid hypothalamic peptide that stimulates pituitary somatotroph cells in vivo. The CJC-1295 sequence corresponds to GHRH(1-29) with substitutions to improve protease resistance, conjugated to a Drug Affinity Complex (DAC) moiety that covalently binds to serum albumin after reconstitution, prolonging circulating half-life in pharmacokinetic model studies. It is used in research settings to study the GHRH–GH axis signaling dynamics and receptor binding kinetics.
- Analogue of GHRH(1-29) — the biologically active fragment of the 44-amino-acid hypothalamic hormone
- DAC moiety enables covalent binding to serum albumin for extended half-life in PK studies
- Amino acid substitutions at positions 2, 8, 15, and 27 increase resistance to dipeptidyl peptidase IV (DPP-IV)
- Endogenous GHRH is secreted in pulsatile fashion from the arcuate nucleus of the hypothalamus
- Lyophilized; reconstituted with bacteriostatic water for in vitro or animal model studies
- Strictly for in vitro and animal model research — not for human or veterinary use
Peer-reviewed research
All products sold by Next Level Research LLC are intended for laboratory and research use only. Not for human or animal consumption. Not a drug, food, or cosmetic. No therapeutic claims are made.