GLOW

Compound Profile

Class

Multi-Peptide Research Blend (Angiogenic / ECM Remodeling)

Origin

Three synthetically manufactured research peptides: BPC-157 (sequence derived from gastric protective protein), TB-500 (synthetic Thymosin Beta-4 analogue), and GHK-Cu (naturally occurring copper-binding tripeptide)

Structure

BPC-157: 15 amino acids · Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val · MW ~1,419 Da TB-500 (Tβ4): 43 amino acids · N-terminally acetylated · MW ~4,964 Da GHK-Cu: Gly-His-Lys · Cu²⁺ chelate complex · MW ~340 Da

Purity

99.5%

Format

Lyophilized powder

Lot

NLR-202606

Overview

GLOW is a lyophilized research blend combining three peptide compounds that have been independently studied in preclinical models. BPC-157 is a 15-amino acid synthetic pentadecapeptide whose sequence is derived from a gastroprotective protein fraction; it has been investigated in cell culture and animal models for effects on angiogenic signaling, nitric oxide pathways, and cytoprotection. TB-500 is a synthetic analogue of Thymosin Beta-4 (Tβ4), an endogenous 43-amino acid peptide that regulates actin sequestration via G-actin binding; Tβ4 has been studied for roles in cellular migration, wound healing, and angiogenesis in preclinical models. GHK-Cu is a naturally occurring copper-chelating tripeptide studied for extracellular matrix remodeling and gene expression modulation in fibroblast systems. This combination is formulated as a lyophilized powder for in vitro and preclinical laboratory research only; each component targets complementary pathways in tissue biology research.

Key Facts

• BPC-157: synthetic 15-AA pentadecapeptide; investigated in rodent wound and gastroprotection models for angiogenic effects via VEGFR2 and FAK–paxillin signaling
• TB-500 (Tβ4): binds G-actin with high affinity (Kd ~0.5 µM), sequestering monomeric actin and modulating cytoskeletal dynamics in cell migration assays
• Thymosin Beta-4 is naturally expressed in most nucleated cells at high concentration; the synthetic analogue TB-500 mimics its actin-binding domain for research use
• GHK-Cu chelates Cu²⁺ with a formation constant of ~10¹⁶ M⁻¹ and has been studied for modulation of collagen, elastin, and glycosaminoglycan synthesis in fibroblast models
• All three components are independently studied in published preclinical literature; combination effects in this formulation have not been studied in controlled published trials
• Lyophilized blend; reconstitute with bacteriostatic water for in vitro use only
• For research use only — not for human or veterinary administration

Published Research