Research Use Only · Not for Human Consumption · For Laboratory & Research Purposes
NLP-3 (RT)
Incretin Mimetic Analogue (Research Tagged)

NLP-3 (RT)

Synthetic 39-amino acid peptide with binding affinity for GIP, GLP-1, and glucagon receptor subtypes. Lyophilized, research-grade.

Compound Profile

Class
Incretin Mimetic Analogue (Research Tagged)
Origin
Synthetic analogue based on the GLP receptor ligand family
Structure
Modified 7-36 amide peptide backbone · Research-tagged variant for receptor binding studies
Purity
98.82%
Format
Lyophilized powder
Lot
NLR-062026

Overview

NLP-3 (RT) is a research-tagged analogue of the glucagon-like peptide family, used in laboratory studies to investigate NLP receptor binding kinetics, signal transduction pathways, and metabolic enzyme activity. The "RT" designation indicates a research tag appended to the peptide for traceability in binding assays. Glucagon-like peptides are incretin hormones naturally produced in the gut; this compound is a synthetic tool for studying those receptor systems in vitro.

Key Facts

  • Member of the proglucagon-derived peptide family
  • GLP receptors (GLP-1R, GLP-2R) are G-protein coupled receptors expressed in multiple tissues
  • Research-tagged variant used for fluorescent or radiometric binding assays
  • Natural GLP-1 is produced by intestinal L-cells in response to nutrient ingestion
  • Used exclusively in in vitro receptor binding and signal transduction research
  • Not approved for any clinical or veterinary application

Certificate of Analysis

Download CoA (PDF)

Published Research

GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review
eClinicalMedicine · 2024 · NCBI
Retatrutide — A Game Changer in Obesity Pharmacotherapy
Biomolecules · 2025 · NCBI
Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis
Proceedings (Baylor University Medical Center) · 2025 · NCBI
For laboratory and research use only. This compound is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease. Not for human or veterinary use.